Win, cover, and run totals for a single regular-season game will be decided across moneyline, multiple totals (9.5 and 8.5), game spreads, first-five-inning spreads, and first-inning scoring markets.

The outcome affects payouts on the winner, whether totals go over or under, and whether teams cover various run-differential lines both early and for the full game.

Starting pitchers, relievers, and projected lineups for the St. Louis Cardinals and Arizona Diamondbacks determine most outcomes.

Managers' pinch-hit and bullpen choices, plus any late scratches, shift first-inning and early-inning spread probabilities quickly.

Pitching matchups and bullpen workloads are the clearest causal levers for moneyline and totals.

Weather, ballpark factors, platoon splits, and recent offensive form push totals and whether a team can pull away before the fifth inning.

Pre-game lineups and announced starting pitchers will move prices the most in the hours before first pitch.

First-inning batter order, late scratches, weather reports, and bullpen warmups during the first two innings are live signals for first-inning and first-five-inning spread markets.