Whether the two teams combine for more or fewer runs than the listed totals and which club covers the posted run margins.
Those outcomes settle the Over/Under lines (10.5–7.5), the ±1.5 and ±2.5 spread contracts, and the first-inning run prop per the official box score.
Starting pitchers largely set the game's early tone through pitch mix, control, and handedness against the opposing lineup.
Cardinals and Athletics hitters, bench bats, catchers' pitch framing, and both bullpens' depth determine late-inning scoring and whether the first inning sees a run.
Pitching matchups, recent form, strikeout and walk rates, and left/right platoon splits change expected scoring and spread probabilities.
Ballpark dimensions, wind and temperature, lineup protection, injuries or late scratches, and bullpen workloads are the main external levers; managerial bullpen pulls can swing totals in-game.
Pre-game starter confirmations and the official lineups, typically posted an hour before first pitch, are immediate signals for matchups and handedness.
Also track weather and wind updates, bullpen usage from recent games, late scratches, first-inning RBI chances, and in-game pitching changes that shift total and spread outcomes.